Cytogenetics Silencing Genomic Imprinting Online Exam Quiz
Cytogenetics Silencing Genomic Imprinting GK Quiz. Question and Answers related to Cytogenetics Silencing Genomic Imprinting. MCQ (Multiple Choice Questions with answers about Cytogenetics Silencing Genomic Imprinting
Genomic imprinting in autosomes is seen in _________________ percent of the genes.
Options
A : 100%
B : 50%
C : 25%
D : <1%
In mice if you delete the Igf2 gene from a female, the progeny will_____________
Options
A : Be smaller
B : Die
C : No major change
D : Be larger
Which of the following doesn’t agree with XIST?
Options
A : It codes for an mRNA that coats the inactive X chromosome into a bar body
B : It is the only gene that is active in inactive X chromosome
C : The embryo cells shows that maternal allele XIST is active over paternal
D : Inactivation is seen in somatic cells
Choose the wrong statement from the following.
Options
A : Maternal Igf2 is methylated to prevent expression
B : Paternal H19 is methylated to avoid expression
C : The enhancer can lead to expression of H19 in maternal gene
D : The enhancer can’t lead to expression of Igf2 in paternal gene
In Igf2 of human ______________ allele is expressed, and Igfr of mice __________ allele is expressed.
Options
A : Maternal, maternal
B : Paternal, paternal
C : Maternal, paternal
D : Paternal, maternal
Choose the wrong statement in the regulation of imprinting.
Options
A : Methylation of the C residues are seen in the CpG islands
B : The methylation prevents binding of the RNA polymerase
C : Genes are methylated at random
D : Deletion of gene with methylated CpG islands will have no effect
In Angelman syndrome we don’t see___________
Options
A : Microcephaly
B : Speech impairment
C : Overeating urge
D : Unprovoked laughter
During _________________ both the H19 alleles are ___________________
Options
A : Oogenesis, inactivated
B : Oogenesis, activated
C : Oogenesis, hyper-activated
D : Spermatogenesis, activated
When the specific non-imprint gene from the chromosome 15 of the mother s missing it leads to _________________
Options
A : Pader Willi syndrome
B : Angelman syndrome
C : Down’s syndrome
D : Klinefelter syndrome
Differential expression of the genetic material depending on its parentage of inheritance gives____________
Options
A : Penetrance
B : Expressivity
C : Imprinting
D : Non-penetrance
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