Question: Which of the following statements about COG is incorrect regarding its features?

Options

A : Currently, there are 4,873 clusters in the COG databases derived from unicellular organisms

B : It is constructed by comparing protein sequences encoded in forty-three completely sequenced genomes, which are mainly from prokaryotes, representing thirty major phylogenetic lineages

C : The interface for sequence searching in the COG database is the COGnitor program, which is based on gapped BLAST

D : It is a protein family database based on structural classification

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