Question: Which of the following is incorrect about Purification of protein complexes followed by mass spectrometry?
Options
A : Isolating protein complexes from cells allows identification of interactions between ensembles of proteins instead of just pairs
B : Systematic purification of complexes on a large scale is done by tagging hundreds of genes with an epitope
C : UnLike in the yeast-two-hybrid assay, this does not involve chimeric genes
D : Affinity purification based on the epitope will then extract all the proteins attached to the bait protein from cell lysates
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