Question: Which of the following is correct regarding the method for prokaryotic operon prediction?
Options
A : It relies on two kinds of information: gene orientation and intergenic distances of a pair of genes of interest and conserved linkage of the genes based on comparative genomic analysis
B : It relies only on the gene orientation and intergenic distances of a pair of genes of interest
C : It relies only on the conserved linkage of the genes based on comparative genomic analysis
D : The prediction cannot be done manually using the rules
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