Question: Which of the following is a wrong statement regarding the conventional determination of open reading frames?
Options
A : Without the use of specialized programs, prokaryotic gene identification can rely on manual determination of ORFs and major signals related to prokaryotic genes
B : Prokaryotic DNA is first subject to conceptual translation in all six possible frames, two frames forward and four frames reverse
C : A stop codon occurs in about every twenty codons by chance in a noncoding region
D : Prokaryotic DNA is first subject to conceptual translation in all six possible frames, three frames forward and three frames reverse
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