Bioinformatics Genome Sequencing Online Exam Quiz
Bioinformatics Genome Sequencing GK Quiz. Question and Answers related to Bioinformatics Genome Sequencing. MCQ (Multiple Choice Questions with answers about Bioinformatics Genome Sequencing
The hierarchical genome sequencing approach is ______
Options
A : entirely dissimilar to the shotgun approach
B : dissimilar to the shotgun approach
C : similar to the shotgun approach, but on a larger scale
D : similar to the shotgun approach, but on a smaller scale
The _____ resolution genome map is the genomic DNA sequence that can be considered as a type of ______ map describing a genome at the single base-pair level.
Options
A : highest, physical
B : lowest, physical
C : highest, cytological
D : lowest, cytological
Which of the following is untrue about DNA sequencing?
Options
A : It is now routinely carried out using the Sanger method
B : This doesn’t make use of DNA polymerases
C : This involves the synthesis of DNA chains of varying length
D : The DNA synthesis is stopped by adding dideoxynucleotides
In hierarchical genome sequencing approach, based on the results of _______ mapping _______of the BAC clones on a chromosome can be determined.
Options
A : physical, the locations and orders
B : physical, only the locations
C : cytological, only the locations
D : physical, only the orders
The shotgun approach _______ sequences clones from _____ of cloned DNA.
Options
A : randomly, one end
B : randomly, both ends
C : specifically, both ends
D : specifically, one end
The hierarchical approach is ____ and _____ than the shotgun approach because it involves an initial clone-based physical mapping step.
Options
A : slower, less costly
B : faster, more costly
C : faster, less costly
D : slower, more costly
Despite the multiple coverage, sometimes certain genomic regions remain unsequenced, mainly owing to cloning difficulties.
Options
A : True
B : False
C :
D :
In DNA sequencing, the fluorescent traces of the DNA sequences are read by a computer program that assigns bases for each peak in a chromatogram.
Options
A : True
B : False
C :
D :
The shotgun approach does not require knowledge of physical mapping of the clone fragments, but rather a robust computer assembly program to join the pieces of random fragments into a single, whole-genome sequence.
Options
A : True
B : False
C :
D :
The whole genome shotgun approach can produce a draft sequence very rapidly because it is based on the direct sequencing approach.
Options
A : True
B : False
C :
D :
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