Drug Biotechnology Bioactivation Tissue Toxicity Online Exam Quiz
Drug Biotechnology Bioactivation Tissue Toxicity GK Quiz. Question and Answers related to Drug Biotechnology Bioactivation Tissue Toxicity. MCQ (Multiple Choice Questions with answers about Drug Biotechnology Bioactivation Tissue Toxicity
Which of the following statement rightly states “bioactivation”?
Options
A : Formation of high reactive metabolites which interact with tissues to precipitate toxic compounds
B : Formation chelating agents
C : Formation of enzymes which can lyse toxic compounds
D : Stimulating the immune systems to initiate the formation of t cells
Which of the following will be an example of inorganic free radicle?
Options
A : H2O2 and O2–
B : Aflatoxin
C : Quinones
D : Benzopyrene
Which of the following is an example of electrophiles?
Options
A : Thalidomide
B : Aflatoxin
C : Epoxides
D : Benzopyrene
Which xenobiotics yield free radicles on metabolic activation?
Options
A : Thalidomide
B : Aflatoxin
C : Quinones
D : Benzopyrene
What is the body’s defence against electrophiles?
Options
A : Their inactivation by conjugation with glucagon
B : Their inactivation by conjugation with glutamine
C : Their inactivation by conjugation with glucuronic acid
D : Their inactivation by conjugation with glutathione
How are electrophiles generated?
Options
A : Through cytochrome P-450 system
B : NADPH cytochrome P-450 reductase
C : Different Flavin containing reductase
D : Through cytochrome P-350 system
How are free radicals generated in the human body?
Options
A : Through cytochrome P-450 system
B : NADPH cytochrome P-450 reductase
C : NADPH reductase
D : Through cytochrome P-350 system
Electrophiles are deficient of pair of electrons and free radicals contain an odd number of electrons.
Options
A : True
B : False
C :
D :
Free radicals are more dangerous than electrophiles.
Options
A : True
B : False
C :
D :
Bioavailability of glutathione in the body doesn’t determine the threshold of a toxic response.
Options
A : True
B : False
C :
D :
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