Drug Biotechnology Applications Prodrug Online Exam Quiz
Drug Biotechnology Applications Prodrug GK Quiz. Question and Answers related to Drug Biotechnology Applications Prodrug. MCQ (Multiple Choice Questions with answers about Drug Biotechnology Applications Prodrug
Which of the following will be a pharmaceutical application of prodrugs?
Options
A : Enhancement of bioavailability
B : Reduction of toxicity
C : Improvement of odour
D : Site-specific drug delivery
Which one of the following will be an example of changing the physical form of the drug to get a prodrug?
Options
A : Ethyl mercaptan to 1,3-Diesters
B : Trichloroethanol to p-Acetamidobenzene ester
C : Ethyl mercaptan to phthalate esters
D : Chloramphenicol to palmitate ester
Which of the following will not be a limitation for prodrug design?
Options
A : Formation of toxic product
B : An inert carrier can be cleaved off forming toxic product
C : Product cleaving off before reaching the target site
D : The cleaving of the carrier is also site-specific
Which of the following reduces the pain of injection?
Options
A : If the drug precipitates
B : If the drug penetrates to the surrounding areas
C : If the solution is strongly acidic
D : More water-soluble drug
Which of the following will be the pharmacokinetic application of prodrugs?
Options
A : Improvement of taste
B : Improvement of odour
C : Site-specific drug delivery
D : Reduction in GI irritation
How improvement of a drug in case of taste is done?
Options
A : Injecting the drug so no taste related problems
B : Reducing the drug solubility in the saliva
C : Lower affinity for the taste receptors and making the drug sweet
D : Reducing drug solubility in saliva and lower affinity for taste receptors
Why lipophilic drugs are absorbed easily?
Options
A : Less hydrolysed
B : Favours passive diffusion
C : Dissolution rate high
D : Can easily merge with the cell membrane
Which one of these is the best way to preserve drugs for intravenous use?
Options
A : Lyophilisation
B : Drying
C : Freezing
D : In solution form
Which of the following is not a disadvantage of site-specific drug delivery?
Options
A : May lead to toxic effects on other non-target tissues
B : May get diluted
C : Less distribution time
D : No penetrable to the target tissue
How to prevent hepatic first-pass metabolism for corticosteroids?
Options
A : Providing intravenously
B : Providing orally
C : Form esters and ether products
D : By enhancing lipophilicity
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