Question: Which of the following is incorrect about Multiple Structure Alignment?

Options

A : The alignment strategy is different than the Clustal sequence alignment using a progressive approach

B : All structures are first compared in a pairwise fashion

C : A distance matrix is developed based on structure similarity scores such as RMSD

D : The aligned structures create a median structure that allows other structures to be progressively added for comparison based on the hierarchy described in the guide tree

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