Question: Which of the following is false in case of the database Pfam and its algorithm?
Options
A : Each motif or domain is represented by an HMM profile generated from the seed alignment of a number of conserved homologous proteins
B : Since the probability scoring mechanism is more complex in HMM than in a profile-based approach the use of HMM yields further increases in sensitivity of the database matches
C : Pfam-B only contains sequence families not covered in Pfam
D : The functional annotation of motifs in Pfam-A is often related to that in UNIPROT
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