Drug Biotechnology Ph Partition Hypothesis Online Exam Quiz
Drug Biotechnology Ph Partition Hypothesis GK Quiz. Question and Answers related to Drug Biotechnology Ph Partition Hypothesis. MCQ (Multiple Choice Questions with answers about Drug Biotechnology Ph Partition Hypothesis
What should be the range of oil/water partition coefficient of any drug?
Options
A : 1-2
B : 3-4
C : 2-3
D : 1-3
What is the pH range of the stomach?
Options
A : 1-4
B : 5-8
C : 1-3
D : 1-8
What is the pH range of the intestine?
Options
A : 4-5
B : 1-3
C : 1-8
D : 5-8
Which one of these is not an example of a basic drug with pKa range 5-11?
Options
A : Cromolyn
B : Imipramine
C : Amitriptyline
D : Chloroquine
Example of a drug which has PKa > 11 is ________
Options
A : Cromolyn
B : Imipramine
C : Amitriptyline
D : Mecamylamine
Which one of these is an example of a strong acid drug?
Options
A : Diazepam
B : Ibuprofen
C : Cromolyn
D : Aspirin
Nitrazepam a weak base, will be in which form in the stomach?
Options
A : Ionized form mostly
B : Non-ionized form mostly
C : Half ionized and half no ionized
D : Will form aggregate
Ibuprofen a weak acid, in the stomach will be present in which of the given form?
Options
A : Ionized form mostly
B : Non-ionized form mostly
C : Half ionized and half no ionized
D : Will form aggregate
Heroin with pKa 7.8 will be in which form in intestinal pH?
Options
A : Ionized form mostly
B : Unionized form mostly
C : Half ionized and half no ionized
D : Will form aggregate
Which of the following equations correct for Henderson-Hasselbach equation for weak acids?
Options
A : PH = pKa – log (Unionized drug concentration /Ionized drug concentration)
B : PH = pKa – log (Ionized drug concentration/ Unionized drug concentration)
C : PH = pKa + log (Ionized drug concentration/ Unionized drug concentration)
D : PH = pKa + log (Unionized drug concentration /Ionized drug concentration)
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