Drug Biotechnology One Two Compartment Open Model Online Exam Quiz

Drug Biotechnology One Two Compartment Open Model GK Quiz. Question and Answers related to Drug Biotechnology One Two Compartment Open Model. MCQ (Multiple Choice Questions with answers about Drug Biotechnology One Two Compartment Open Model

To have a plasma distribution value of 900 ml and plasma drug concentration to be 1.2 mg/ml what should be the amount of drug that should be given to the patient?

Options

A : 1080 ml

B : 1080 g

C : 1080 mg

D : 1g/ml

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How much time does an intravenously administered drug take to complete a complete circulation?

Options

A : 5-8 min

B : 7-10 min

C : 1-3 min

D : 1 min

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The i.v. bolus dosage is 500mg and the plasma drug concentration is 0.8 mg/ml. What should be the volume of distribution?

Options

A : 625 mg/ml

B : 625 l

C : 625 ml

D : 0.0016 mg/ml

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At which of the four marked points of the plasma drug concentration versus time graph, absorption rate = elimination rate?

Options

A : a

B : b

C : c

D : d

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What is the equation to find out the apparent volume of distribution?

Options

A : Amount of drug in the body/plasma drug concentration

B : Plasma drug concentration/amount of drug in the body

C : 1 / plasma drug concentration

D : 1 / Amount of drug in the body

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Which organ comprises the peripheral compartment in a two compartment model?

Options

A : Liver

B : Lungs

C : Kidneys

D : Muscles

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Which organs comprise the central compartment in a two compartment model?

Options

A : Muscles

B : Skin

C : Adipose

D : Liver

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In the equation log C = log Co – KEt/2.303, what does Co stand for _______

Options

A : Plasma drug concentration after 60 min of i.v. injection

B : Plasma drug concentration after 15 min of i.v. injection

C : Plasma drug concentration after 30 min of i.v. injection

D : Plasma drug concentration immediately after i.v. injection

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What is the equation to find out hepatic clearance?

Options

A : Plasma drug concentration/rate of elimination by the kidney

B : Rate of elimination by kidney/plasma drug concentration

C : 1 / rate of elimination by the kidney

D : 1 / plasma drug concentration

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What does the word “open” mean in the one compartment open model?

Options

A : The drug easily enters

B : The drug readily mixes with the blood

C : Unidirectional input and output

D : Easy absorption

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