Drug Biotechnology Limitations Ph Partition Hypothesis Online Exam Quiz
Drug Biotechnology Limitations Ph Partition Hypothesis GK Quiz. Question and Answers related to Drug Biotechnology Limitations Ph Partition Hypothesis. MCQ (Multiple Choice Questions with answers about Drug Biotechnology Limitations Ph Partition Hypothesis
What are the major stability problems which result in poor bioavailability of any orally administered drugs?
Options
A : Acidic degradation
B : Degradation by salivary amylase
C : Degradation of the drug in inactive form
D : Interaction with the excipients and degradation in an inactive form
What helps the ionized drug molecules to pass through the cell membrane passively?
Options
A : Different pH
B : Polar group
C : Large lipophilic group
D : Hydration
According to the pH-partition theory which form of the drug gets absorbed mostly?
Options
A : Hydrated form
B : Aggregated form
C : Ionised
D : Unionised
What could be the reason that irrespective of pH any drug gets absorbed mostly from the intestine?
Options
A : More surface area
B : Long residence time
C : Large surface area and long residence time
D : Large surface area, long residence time, basic pH
What will be in the place of ‘?’ in the given picture?
Options
A : Plasma layer
B : Aqueous unstirred diffusion layer
C : Lipid membrane
D : Blood vessel
Which one of these options is not one of the limitations of pH-partition theory?
Options
A : Presence if virtual membrane pH
B : Absorption of ionized drugs
C : Influence of GI surface area
D : Dissolution rate
A microclimate pH, different from the luminal pH exists at the membrane surface.
Options
A : True
B : False
C :
D :
Acidic drugs are best absorbed through the stomach and basic drugs are best absorbed through the intestine.
Options
A : True
B : False
C :
D :
Drug having a small partition coefficient can rapidly penetrate the lipid membrane but diffusion through the unstirred water layer is a rate-limiting step.
Options
A : True
B : False
C :
D :
Drug Biotechnology Absorption Drugs Non Oral Extravascular Sites 1 more Online Exam Quiz
Drug Biotechnology Indian Drug Regulations
Drug Biotechnology Interview Experienced
Drug Biotechnology Interview Freshers
Drug Biotechnology Measurement Bioavailability
Drug Biotechnology Mechanism Drug Interactions