Bioinformatics Methods Online Exam Quiz
Bioinformatics Methods GK Quiz. Question and Answers related to Bioinformatics Methods. MCQ (Multiple Choice Questions with answers about Bioinformatics Methods
When the two sequences have substantial regions of similarity, many dots line up to form contiguous _______ lines.
Options
A : crossings on
B : horizontal
C : diagonal
D : vertical
In a dot matrix, two sequences to be compared are written in the _____________ of the matrix.
Options
A : horizontal and vertical axes
B : 2 parallel horizontal axes
C : 2 parallel vertical axes
D : horizontal axis (one preceding another)
A problem exists when comparing _____ sequences using the dot matrix method, namely, the _______
Options
A : small, amplification
B : large, amplification
C : small, high noise level
D : large, high noise level
Which of the following is untrue about dot plot method and its applications?
Options
A : This method gives a direct visual statement of the relationship between two sequences
B : One of its advantages is the identification of sequence repeat regions based on the presence of parallel diagonals of the same size vertically or horizontally in the matrix
C : It is not useful in identifying chromosomal repeats
D : The method can be used in identifying nucleic acid secondary structures through detecting self-complementarity of a sequence
A sequence can be aligned with itself to identify internal repeat elements.
Options
A : True
B : False
C :
D :
Alignment algorithms, both global and local, are fundamentally similar and only differ in the optimization strategy used in aligning similar residues.
Options
A : True
B : False
C :
D :
If the selected window size is too long, sensitivity of the alignment is lost.
Options
A : True
B : False
C :
D :
The overall goal of pair wise sequence alignment is to find the best pairing of two sequences, such that there is maximum correspondence among residues.
Options
A : True
B : False
C :
D :
In local alignment, the two sequences to be aligned cannot be of unequal lengths.
Options
A : True
B : False
C :
D :
Self complementarity of DNA sequences cannot be identified using a dot plot.
Options
A : True
B : False
C :
D :
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