Question: Which of the following wrong about HMM GENE?

Options

A : It is also an HMM-based web program

B : It uses a criterion called the conditional maximum likelihood to discriminate coding from non-coding features

C : HMM prediction is unbiased toward the locked region

D : If a sequence already has a sub-region identified as coding region, which may be based on similarity with cDNAs or proteins in a database, these regions are locked as coding regions

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