Question: Which of the following is untrue regarding Expectation Maximization algorithm?

Options

A : An initial guess is made as to the location and size of the site of interest in each of the sequences, and these parts of the sequence are aligned

B : The alignment provides an estimate of the base or amino acid composition of each column in the site

C : The column-by-column composition of the site already available is used to estimate the probability of finding the site at any position in each of the sequences

D : The row-by-column composition of the site already available is used to estimate the probability

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